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eNews from Friday, February 13, 2009

Combination of Soy With a Probiotic or Prebiotic Food Significantly Reduces Cholesterol: Australian Study

Blood Weekly -- February 19, 2009 -- Research findings, 'Dietary combination of soy with a probiotic or prebiotic food significantly reduces total and LDL cholesterol in mildly hypercholesterolaemic subjects,' are discussed in a new report (see also http://www.newsrx.com/library/topics/Life-Sciences.html). According to a study from Australia, "We hypothesized that a dietary combination of soy with either a probiotic (yoghurt) or a prebiotic (resistant starch) would result in enhanced lipid-lowering effects compared with a control soy diet, possibly via improvements in isoflavone bioavailability. Mildly hypercholesterolaemic subjects (men and post-menopausal women) older than 45 years were recruited via the local media."

"Thirty-six subjects commenced the study; five withdrew. Soy+probiotic significantly decreased total cholesterol (4.7±2.0%; p=0.038) and soy+prebiotic significantly decreased total and low-density lipoprotein cholesterol (5.5±1.6%; p=0.003 and 7.3±2.2%; p=0.005, respectively). The bioavailabilities of daidzein, genistein or equol were not affected by probiotic or prebiotic consumption or associated with lipid changes," wrote T.A. Larkin and colleagues, University of Wollongong, Department of Biomedical Science.

The researchers concluded: "Dietary combination of soy with either a probiotic or a prebiotic resulted in significant lipid lowering, not related to isoflavone bioavailability."

Larkin and colleagues published their study in European Journal of Clinical Nutrition (Dietary combination of soy with a probiotic or prebiotic food significantly reduces total and LDL cholesterol in mildly hypercholesterolaemic subjects. European Journal of Clinical Nutrition, 2009;63(2):238-45).

For more information, contact T.A. Larkin, University of Wollongong, Dept. of Biomedical Science, Wollongong, New South Wales, Australia.

Publisher contact information for the European Journal of Clinical Nutrition is: Nature Publishing Group, 345 Park Avenue South, New York, NY 10010-1707, USA.

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