eNews from Friday, January 7, 2011

Soy Protein Does Reduce Cholesterol When Added to the Diet, Confirms New Canadian Study

Science Letter: January 11, 2011 12:01:00 AM EST -- Current study results from the report, 'Soy protein reduces serum cholesterol by both intrinsic and food displacement mechanisms,' have been published. "The apparently smaller LDL cholesterol (LDL-C)-lowering effect of soy in recent studies has prompted the U.S. FDA to reexamine the heart health claim previously allowed for soy products," scientists writing in the Journal of Nutrition report (see also Life Science).

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"We therefore attempted to estimate the intrinsic and extrinsic (displacement) potential of soy in reducing LDL-C to determine whether the heart health claim for soy continues to be justified. The intrinsic effect of soy was derived from a meta-analysis using soy studies (20-133 g/d soy protein) included in the recent AHA Soy Advisory. The extrinsic effect of soy in displacing foods higher in saturated fat and cholesterol was estimated using predictive equations for LDL-C and NHANES III population survey data with the substitution of 13-58 g/d soy protein for animal protein foods. The meta-analysis of the AHA Soy Advisory data gave a mean LDL-C reduction of 0.17 mmol/L (n=22; p<0.0001) or 4.3% for soy, which was confirmed in 11 studies reporting balanced macronutrient profiles. The estimated displacement value of soy (13-58 g/d) using NHANES III population survey data was a 3.6-6.0% reduction in LDL-C due to displacement of saturated fats and cholesterol from animal foods. The LDL-C reduction attributable to the combined intrinsic and extrinsic effects of soy protein foods ranged from 7.9 to 10.3%," wrote D.J. Jenkins and colleagues, St. Michael's Hospital, Department of Medicine.

The researchers concluded: "Thus, soy remains one of a few food components that reduces serum cholesterol (>4%) when added to the diet."

Jenkins and colleagues published their study in the Journal of Nutrition (Soy protein reduces serum cholesterol by both intrinsic and food displacement mechanisms. Journal of Nutrition, 2010;140(12):2302S-2311S).

Additional information can be obtained by contacting D.J. Jenkins, St. Michael's Hospital, St. Michael's Hospital, Dept. of Medicine, Toronto, Ontario, Canada.

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eNews from Friday, January 7, 2011

Soy Protein Does Reduce Cholesterol When Added to the Diet, Confirms New Canadian Study

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